Reciprocal negative regulation between the tumor suppressor protein p53 and B cell CLL/lymphoma 6 (BCL6) via control of caspase-1 expression

Even in the face of physiological DNA damage or expression of the tumor suppressor protein p53, B cell CLL/lymphoma 6 (BCL6) increases proliferation and antagonizes apoptotic responses in B cells. BCL6 represses TP53 transcription and also appears to inactivate p53 at the protein level, and addition...

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Udgivet i:J Biol Chem
Main Authors: Kim, Min-Kyeong, Song, Ji-Yang, Koh, Dong-In, Kim, Jin Young, Hatano, Masahiko, Jeon, Bu-Nam, Kim, Min-Young, Cho, Su-Yeon, Kim, Kyung-Sup, Hur, Man-Wook
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322868/
https://ncbi.nlm.nih.gov/pubmed/30409904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004204
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