Jakinibs for the Treatment of Immunodysregulation in Patients with Gain of Function STAT1 or STAT3 Mutations

Treatment of the autoimmune and immune-dysregulatory features of patients with STAT1 GOF or STAT3 GOF disease remains challenging. Jakinibs have been used to treat the severe immune-dysregulation in patients with either STAT1 GOF or STAT3 GOF mutations.

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Forbes, Lisa R., Vogel, Tiphanie P., Cooper, Megan A., Castro-Wagner, Johana, Schussler, Edith, Weinacht, Katja G., Plant, Ashley S., Su, Helen C., Allenspach, Eric J., Slatter, Mary, Abinun, Mario, Lilic, Desa, Cunningham-Rundles, Charlotte, Eckstein, Olive, Olbrich, Peter, Guillerman, R. Paul, Patel, Niraj C., Demirdag, Yesim Y., Zerbe, Christa, Freeman, Alexandra F., Holland, Steven M., Szabolcs, Paul, Gennery, Andrew, Torgerson, Troy R., Milner, Joshua D., Leiding, Jennifer W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322659/
https://ncbi.nlm.nih.gov/pubmed/30092289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.07.020
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