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A guide to maximizing the therapeutic potential of protein-polymer conjugates by rational design
Proteins are an important class of therapeutics that have advantages including high target specificity, but challenges to their use include rapid clearance and low physical stability. Conjugation of synthetic polymers is an effective approach to address the drawbacks and enhance other properties suc...
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出版年: | Chem Soc Rev |
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主要な著者: | , |
フォーマット: | Artigo |
言語: | Inglês |
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2018
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322549/ https://ncbi.nlm.nih.gov/pubmed/30443654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cs00606g |
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