Effects of vadadustat on hemoglobin concentrations in patients receiving hemodialysis previously treated with erythropoiesis-stimulating agents

BACKGROUND: Vadadustat, an inhibitor of hypoxia-inducible factor prolyl-4-hydroxylase domain dioxygenases, is an oral investigational agent in development for the treatment of anemia secondary to chronic kidney disease. METHODS: In this open-label Phase 2 trial, vadadustat was evaluated in 94 subjec...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Haase, Volker H, Chertow, Glenn M, Block, Geoffrey A, Pergola, Pablo E, deGoma, Emil M, Khawaja, Zeeshan, Sharma, Amit, Maroni, Bradley J, McCullough, Peter A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322440/
https://ncbi.nlm.nih.gov/pubmed/29672740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfy055
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