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Lobar evenness of deposition/retention in rat lungs of inhaled silver nanoparticles: an approach for reducing animal use while maximizing endpoints

BACKGROUND: Information on particle deposition, retention and clearance are important for the evaluation of the risk of inhaled nanomaterials to human health. Recent revised OECD inhalation toxicity test guidelines require to evaluate the lung burden of nanomaterials after rodent subacute and subchr...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Park, Jung Duck, Kim, Jin Kwon, Jo, Mi Seong, Kim, Young Hun, Jeon, Ki Soo, Lee, Ji Hyun, Faustman, Elaine M., Lee, Hong Ku, Ahn, Kangho, Gulumian, Mary, Oberdörster, Günter, Yu, Il Je
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322301/
https://ncbi.nlm.nih.gov/pubmed/30616672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-018-0286-9
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