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Idiopathic Pulmonary Fibrosis Is a Genetic Disease Involving Mucus and the Peripheral Airways
Idiopathic pulmonary fibrosis (IPF) is localized to the lung, is characterized by a pattern of heterogeneous, subpleural patches of fibrotic, remodeled lung, and is associated with a median survival of 3–5 years after diagnosis. A common gain-of-function MUC5B promoter variant, rs35705950, is the st...
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| Udgivet i: | Ann Am Thorac Soc |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322034/ https://ncbi.nlm.nih.gov/pubmed/30431344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201802-144AW |
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