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Idiopathic Pulmonary Fibrosis Is a Genetic Disease Involving Mucus and the Peripheral Airways

Idiopathic pulmonary fibrosis (IPF) is localized to the lung, is characterized by a pattern of heterogeneous, subpleural patches of fibrotic, remodeled lung, and is associated with a median survival of 3–5 years after diagnosis. A common gain-of-function MUC5B promoter variant, rs35705950, is the st...

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Detalhes bibliográficos
Publicado no:Ann Am Thorac Soc
Autor principal: Schwartz, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322034/
https://ncbi.nlm.nih.gov/pubmed/30431344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201802-144AW
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