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Idiopathic Pulmonary Fibrosis Is a Genetic Disease Involving Mucus and the Peripheral Airways

Idiopathic pulmonary fibrosis (IPF) is localized to the lung, is characterized by a pattern of heterogeneous, subpleural patches of fibrotic, remodeled lung, and is associated with a median survival of 3–5 years after diagnosis. A common gain-of-function MUC5B promoter variant, rs35705950, is the st...

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Bibliografiske detaljer
Udgivet i:Ann Am Thorac Soc
Hovedforfatter: Schwartz, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322034/
https://ncbi.nlm.nih.gov/pubmed/30431344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201802-144AW
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