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Functional Studies of Single-Nucleotide Polymorphisms Suggest Heterogeneity in Chronic Obstructive Pulmonary Disease due to Susceptibility of Different Cell Types

Chronic obstructive pulmonary disease (COPD) is a syndrome that comprises several lung pathologies, but subphenotyping the various disease subtypes has not been successful. We found that a single-nucleotide polymorphism (SNP) within the proline-rich domain of transformation-related protein 53 (TP53)...

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Detalhes bibliográficos
Publicado no:Ann Am Thorac Soc
Main Authors: Tesfaigzi, Yohannes, Petersen, Hans, Celli, Bartolome, Owen, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322001/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201806-437MG
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