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Hybrid Three-Dimensional Lung Tissue Cultures to Improve Ex Vivo Models of Chronic Obstructive Pulmonary Disease

Rationale: Continued reliance on preclinical animal models and traditional human cell culture experiments conducted on supraphysiologically stiff surfaces in two dimensions often limits the translation of cellular and molecular mechanistic findings into effective therapies for patients suffering fro...

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Detalhes bibliográficos
Publicado no:Ann Am Thorac Soc
Main Authors: Bailey, Kolene E., D’Ovidio, Tyler J., Manning, Nicole, Koenigshoff, Melanie, Magin, Chelsea M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322000/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201806-422MG
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