Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition

The hemagglutinin (HA), a glycoprotein on the surface of influenza A virus (IAV), initiates the virus life cycle by binding to terminal sialic acid (SA) residues on host cells. The HA gradually accumulates amino acid substitutions that allow IAV to escape immunity through a mechanism known as antige...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Santos, Jefferson J. S., Abente, Eugenio J., Obadan, Adebimpe O., Thompson, Andrew J., Ferreri, Lucas, Geiger, Ginger, Gonzalez-Reiche, Ana S., Lewis, Nicola S., Burke, David F., Rajão, Daniela S., Paulson, James C., Vincent, Amy L., Perez, Daniel R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Genetic Diversity and Evolution
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321904/
https://ncbi.nlm.nih.gov/pubmed/30355680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01413-18
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