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Novel Clofarabine-Based Combinations with Polyphenols Epigenetically Reactivate Retinoic Acid Receptor Beta, Inhibit Cell Growth, and Induce Apoptosis of Breast Cancer Cells

An epigenetic component, especially aberrant DNA methylation pattern, has been shown to be frequently involved in sporadic breast cancer development. A growing body of literature demonstrates that combination of agents, i.e. nucleoside analogues with dietary phytochemicals, may provide enhanced ther...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lubecka, Katarzyna, Kaufman-Szymczyk, Agnieszka, Cebula-Obrzut, Barbara, Smolewski, Piotr, Szemraj, Janusz, Fabianowska-Majewska, Krystyna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321577/
https://ncbi.nlm.nih.gov/pubmed/30544666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123970
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