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Search of Allosteric Inhibitors and Associated Proteins of an AKT-like Kinase from Trypanosoma cruzi

Proteins associated to the PI3K/AKT/mTOR signaling pathway are widely used targets for cancer treatment, and in recent years they have also been evaluated as putative targets in trypanosomatids parasites, such as Trypanosoma cruzi. Here, we performed a virtual screening approach to find candidates t...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Ochoa, Rodrigo, Rocha-Roa, Cristian, Marín-Villa, Marcel, Robledo, Sara M., Varela-M, Rubén E.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321509/
https://ncbi.nlm.nih.gov/pubmed/30544836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123951
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