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The Role of Combined Penetration Enhancers in Nasal Microspheres on In Vivo Drug Bioavailability

Microspheres based on both methyl-β-cyclodextrins and chitosan were prepared by spray-drying as nasal formulations of a model polar drug to analyze, firstly, how the composition of the carrier affects drug permeation across synthetic membranes and, secondly, how it induces systemic or brain delivery...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Rassu, Giovanna, Ferraro, Luca, Pavan, Barbara, Giunchedi, Paolo, Gavini, Elisabetta, Dalpiaz, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321492/
https://ncbi.nlm.nih.gov/pubmed/30373187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040206
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