Dissection of the Structural Features of a Fungicidal Antibody-Derived Peptide

The synthetic peptide T11F (TCRVDHRGLTF), derived from the constant region of human IgM antibodies, proved to exert a significant activity in vitro against yeast strains, including multidrug resistant isolates. Alanine substitution of positively charged residues led to a decrease in candidacidal act...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Pertinhez, Thelma A., Ciociola, Tecla, Giovati, Laura, Magliani, Walter, Belletti, Silvana, Polonelli, Luciano, Conti, Stefania, Spisni, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321458/
https://ncbi.nlm.nih.gov/pubmed/30487461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123792
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