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Development of Spermatogenesis In Vitro in Three-Dimensional Culture from Spermatogonial Cells of Busulfan-Treated Immature Mice

Aggressive chemotherapy may lead to permanent male infertility. Prepubertal males do not generate sperm, but their testes do contain spermatogonial cells (SPGCs) that could be used for fertility preservation. In the present study, we examined the effect of busulfan (BU) on the SPGCs of immature mice...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: AbuMadighem, Ali, Solomon, Ronnie, Stepanovsky, Alina, Kapelushnik, Joseph, Shi, QingHua, Meese, Eckart, Lunenfeld, Eitan, Huleihel, Mahmoud
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321353/
https://ncbi.nlm.nih.gov/pubmed/30501072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123804
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