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Evaluation of [(68)Ga]Ga-DOTA-TCTP-1 for the Detection of Metalloproteinase 2/9 Expression in Mouse Atherosclerotic Plaques

Background: The expression of matrix metalloproteinases 2/9 (MMP-2/9) has been implicated in arterial remodeling and inflammation in atherosclerosis. We evaluated a gallium-68 labeled peptide for the detection of MMP-2/9 in atherosclerotic mouse aorta. Methods: We studied sixteen low-density lipopro...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kiugel, Max, Hellberg, Sanna, Käkelä, Meeri, Liljenbäck, Heidi, Saanijoki, Tiina, Li, Xiang-Guo, Tuomela, Johanna, Knuuti, Juhani, Saraste, Antti, Roivainen, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321344/
https://ncbi.nlm.nih.gov/pubmed/30513758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123168
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