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Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches

Chagas disease is one of the primary causes of heart diseases accounting to 50,000 lives annually and is listed as the neglected tropical disease. Because the currently available therapies have greater toxic effects with higher resistance, there is a dire need to develop new drugs to combat the dise...

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Vydáno v:Molecules
Hlavní autoři: Rampogu, Shailima, Lee, Gihwan, Baek, Ayoung, Son, Minky, Park, Chanin, Zeb, Amir, Yoon, Sang Hwa, Park, Suhyeon, Lee, Keun Woo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321154/
https://ncbi.nlm.nih.gov/pubmed/30469538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123054
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