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Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches

Chagas disease is one of the primary causes of heart diseases accounting to 50,000 lives annually and is listed as the neglected tropical disease. Because the currently available therapies have greater toxic effects with higher resistance, there is a dire need to develop new drugs to combat the dise...

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Bibliografske podrobnosti
izdano v:	Molecules
Main Authors:	Rampogu, Shailima, Lee, Gihwan, Baek, Ayoung, Son, Minky, Park, Chanin, Zeb, Amir, Yoon, Sang Hwa, Park, Suhyeon, Lee, Keun Woo
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI 2018
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6321154/ https://ncbi.nlm.nih.gov/pubmed/30469538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123054
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Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches

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