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Discovery of Non-Peptidic Compounds against Chagas Disease Applying Pharmacophore Guided Molecular Modelling Approaches

Chagas disease is one of the primary causes of heart diseases accounting to 50,000 lives annually and is listed as the neglected tropical disease. Because the currently available therapies have greater toxic effects with higher resistance, there is a dire need to develop new drugs to combat the dise...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Rampogu, Shailima, Lee, Gihwan, Baek, Ayoung, Son, Minky, Park, Chanin, Zeb, Amir, Yoon, Sang Hwa, Park, Suhyeon, Lee, Keun Woo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321154/
https://ncbi.nlm.nih.gov/pubmed/30469538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123054
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