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Complementary Quantitative Structure–Activity Relationship Models for the Antitrypanosomal Activity of Sesquiterpene Lactones

Three complementary quantitative structure–activity relationship (QSAR) methodologies, namely, regression modeling based on (i) “classical” molecular descriptors, (ii) 3D pharmacophore features, and (iii) 2D molecular holograms (HQSAR) were employed on the antitrypanosomal activity of sesquiterpene...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Kimani, Njogu M., Matasyoh, Josphat C., Kaiser, Marcel, Nogueira, Mauro S., Trossini, Gustavo H. G., Schmidt, Thomas J.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321053/
https://ncbi.nlm.nih.gov/pubmed/30467296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123721
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