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Probing the Action of Permeation Enhancers Sodium Cholate and N-dodecyl-β-D-maltoside in a Porcine Jejunal Mucosal Explant System

The small intestinal epithelium constitutes a major permeability barrier for the oral administration of therapeutic drugs with poor bioavailability, and permeation enhancers (PEs) are required to increase the paracellular and/or transcellular uptake of such drugs. Many PEs act as surfactants by pert...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Danielsen, E. Michael, Hansen, Gert H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320951/
https://ncbi.nlm.nih.gov/pubmed/30279382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040172
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