Characterization and Antiproliferative Activity of a Novel 2-Aminothiophene Derivative-β-Cyclodextrin Binary System

The novel 2-aminothiophene derivative 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (6CN) has shown potential anti-proliferative activity in human cancer cell lines. However, the poor aqueous solubility of 6CN impairs its clinical use. This work aimed to develop binary 6CN-β-cyclodextri...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Ferreira, Elayne Barros, da Silva Júnior, Walter Ferreira, de Oliveira Pinheiro, Jonas Gabriel, da Fonseca, Aldilane Gonçalves, Moura Lemos, Telma Maria Araújo, de Oliveira Rocha, Hugo Alexandre, de Azevedo, Eduardo Pereira, Mendonça Junior, Francisco Jaime Bezerra, Neves de Lima, Ádley Antonini
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320897/
https://ncbi.nlm.nih.gov/pubmed/30501061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123130
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