Gut Microbiota-Dependent Trimethylamine N-Oxide Pathway Associated with Cardiovascular Risk in Children with Early-Stage Chronic Kidney Disease

Despite cardiovascular disease (CVD) being the leading cause of morbidity and mortality in chronic kidney disease (CKD), less attention has been paid to subclinical CVD in children and adolescents with early CKD stages. Gut microbiota and their metabolite, trimethylamine N-oxide (TMAO), have been li...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Hsu, Chien-Ning, Lu, Pei-Chen, Lo, Mao-Hung, Lin, I-Chun, Chang-Chien, Guo-Ping, Lin, Sufan, Tain, You-Lin
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320870/
https://ncbi.nlm.nih.gov/pubmed/30469463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123699
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