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In Vitro and In Silico Analyses of Nicotine Release from a Gelisphere-Loaded Compressed Polymeric Matrix for Potential Parkinson’s Disease Interventions

This study aimed to develop a prolonged-release device for the potential site-specific delivery of a neuroprotective agent (nicotine). The device was formulated as a novel reinforced crosslinked composite polymeric system with the potential for intrastriatal implantation in Parkinson’s disease inter...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Kumar, Pradeep, Choonara, Yahya E., du Toit, Lisa C., Singh, Neha, Pillay, Viness
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320845/
https://ncbi.nlm.nih.gov/pubmed/30445765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040233
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