Enantioselective Michael Addition of Aldehydes to Maleimides Organocatalyzed by a Chiral Primary Amine-Salicylamide

A primary amine-salicylamide derived from chiral trans-cyclohexane-1,2-diamine was used as an organocatalyst for the enantioselective conjugate addition of aldehydes, mainly α,α-disubstituted to N-substituted maleimides. The reaction was performed in toluene as a solvent at room temperature. The cor...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Torregrosa-Chinillach, Alejandro, Moragues, Adrien, Pérez-Furundarena, Haritz, Chinchilla, Rafael, Gómez-Bengoa, Enrique, Guillena, Gabriela
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320823/
https://ncbi.nlm.nih.gov/pubmed/30545145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123299
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