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Intracellular Accumulation of Linezolid and Florfenicol in OptrA-Producing Enterococcus faecalis and Staphylococcus aureus

The optrA gene, which confers transferable resistance to oxazolidinones and phenicols, is defined as an ATP-binding cassette (ABC) transporter but lacks transmembrane domains. The resistance mechanism of optrA and whether it involves antibiotic efflux or ribosomal protection remain unclear. In this...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Wang, Yingyu, Li, Xiaowei, Wang, Yang, Schwarz, Stefan, Shen, Jianzhong, Xia, Xi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320770/
https://ncbi.nlm.nih.gov/pubmed/30518106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123195
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