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Adults with septic shock and extreme hyperferritinemia exhibit pathogenic immune variation

Post-hoc subgroup analysis of the negative trial of interleukin-1β receptor antagonist (IL1RA) for septic shock suggested that patients with features of macrophage activation syndrome (MAS) experienced a 50% relative risk reduction for mortality with treatment. Here we seek a genetic basis for this...

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Publicat a:Genes Immun
Autors principals: Kernan, Kate F., Ghaloul-Gonzalez, Lina, Shakoory, Bita, Kellum, John A., Angus, Derek C., Carcillo, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320733/
https://ncbi.nlm.nih.gov/pubmed/29977033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-018-0030-3
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