Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations

BACKGROUND: The innate immune system senses viral infection through pattern recognition receptors (PRRs), leading to type I interferon production. The role of type I interferon and PPRs in rhinovirus-induced asthma exacerbations in vivo are uncertain. OBJECTIVES: We sought to compare bronchial mucos...

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Udgivet i:J Allergy Clin Immunol
Main Authors: Zhu, Jie, Message, Simon D., Mallia, Patrick, Kebadze, Tatiana, Contoli, Marco, Ward, Christine K., Barnathan, Elliot S., Mascelli, Mary Ann, Kon, Onn M., Papi, Alberto, Stanciu, Luminita A., Edwards, Michael R., Jeffery, Peter K., Johnston, Sebastian L.
Format: Artigo
Sprog:Inglês
Udgivet: Mosby 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320262/
https://ncbi.nlm.nih.gov/pubmed/29698627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.04.003
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