Assessment of the Abuse Potential of Cebranopadol in Nondependent Recreational Opioid Users: A Phase 1 Randomized Controlled Study

BACKGROUND: Cebranopadol is a nociceptin/orphanin FQ peptide/opioid receptor agonist with central antinociceptive activity. We hypothesize that this novel mechanism of action may lead to a lower risk of abuse compared with pure μ-opioid peptide receptor agonists. METHODS: We conducted a single-dose,...

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Détails bibliographiques
Publié dans:J Clin Psychopharmacol
Auteurs principaux: Göhler, Karin, Sokolowska, Marta, Schoedel, Kerri A., Nemeth, Robert, Kleideiter, Elke, Szeto, Isabella, Eerdekens, Marie-Henriette
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2019
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Original Contributions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319565/
https://ncbi.nlm.nih.gov/pubmed/30531478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0000000000000995
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