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Structural basis for coupling of protein transport and N-glycosylation at the mammalian endoplasmic reticulum
Protein synthesis, transport and N-glycosylation are coupled at the mammalian endoplasmic reticulum (ER) by complex formation of the ribosome, the Sec61 protein-conducting channel and the oligosaccharyltransferase (OST). Here, we used different cryo-electron microscopy approaches to determine struct...
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| Pubblicato in: | Science |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6319373/ https://ncbi.nlm.nih.gov/pubmed/29519914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar7899 |
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