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Sestd1 Encodes a Developmentally Dynamic Synapse Protein That Complexes With BCR Rac1-GAP to Regulate Forebrain Dendrite, Spine and Synapse Formation

SEC14 and Spectrin domain-1 (Sestd1) is a synapse protein that exhibits a striking shift from the presynaptic to postsynaptic space as neurons mature postnatally in the mouse hippocampus. Hippocampal pyramidal neurons from mice with global genetic deletion of Sestd1 have reduced dendrite arbors, spi...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Yang, Xiao Yong, Stanley, Robert E, Ross, Adam P, Robitaille, Aaron M, Gray, John A, Cheyette, Benjamin N R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319175/
https://ncbi.nlm.nih.gov/pubmed/29293918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx333
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