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Cytoplasmic glycoengineering of Apx toxin fragments in the development of Actinobacillus pleuropneumoniae glycoconjugate vaccines

BACKGROUND: Actinobacillus pleuropneumoniae is the causative agent of porcine pleuropneumonia and represents a major burden to the livestock industry. Virulence can largely be attributed to the secretion of a series of haemolytic toxins, which are highly immunogenic. A. pleuropneumoniae also encodes...

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Publicado en:BMC Vet Res
Autores principales: Passmore, Ian J., Andrejeva, Anna, Wren, Brendan W., Cuccui, Jon
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318927/
https://ncbi.nlm.nih.gov/pubmed/30606265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-018-1751-2
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