A gD&gC-substituted pseudorabies virus vaccine strain provides complete clinical protection and is helpful to prevent virus shedding against challenge by a Chinese pseudorabies variant

BACKGROUND: Since 2011, pseudorabies caused by a variant PRV has re-emerged in many Chinese Bartha-K61-vaccinated pig farms. An efficacious vaccine is necessary to control this disease. We described the construction of a gD&gC-substituted pseudorabies virus (PRV B-gD&gC(S)) from the Bartha-K...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Zhang, Chuanjian, Liu, Yamei, Chen, Saisai, Qiao, Yongfeng, Guo, Mingpeng, Zheng, Yating, Xu, Mengwei, Wang, Zhisheng, Hou, Jibo, Wang, Jichun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318912/
https://ncbi.nlm.nih.gov/pubmed/30606159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-018-1766-8
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