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Aspirin inhibits the proliferation of hepatoma cells through controlling GLUT1-mediated glucose metabolism

Aspirin can efficiently inhibit liver cancer growth, but the mechanism is poorly understood. In this study, we report that aspirin modulates glucose uptake through downregulating glucose transporter 1 (GLUT1), leading to the inhibition of hepatoma cell proliferation. Our data showed that aspirin sig...

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Enregistré dans:
Détails bibliographiques
Publié dans:Acta Pharmacol Sin
Auteurs principaux: Liu, Yun-xia, Feng, Jin-yan, Sun, Ming-ming, Liu, Bo-wen, Yang, Guang, Bu, Ya-nan, Zhao, Man, Wang, Tian-jiao, Zhang, Wei-ying, Yuan, Hong-feng, Zhang, Xiao-dong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318307/
https://ncbi.nlm.nih.gov/pubmed/29925918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0014-x
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