Upregulation of CD81 in trophoblasts induces an imbalance of Treg/Th17 cells by promoting IL-6 expression in preeclampsia

The disturbance of maternal immune tolerance to a semiallogeneic fetus is recognized as one of the key pathologies of preeclampsia (PE), in which an imbalance between the inflammation-limiting regulatory T cells (Tregs) and the inflammation-mediating Th17 cells plays an essential role. Previously, w...

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Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Ding, Hailin, Dai, Yimin, Lei, Yi, Wang, Zhiyin, Liu, Dan, Li, Ruotian, Shen, Li, Gu, Ning, Zheng, Mingming, Zhu, Xiangyu, Zhao, Guangfeng, Hu, Yali
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318306/
https://ncbi.nlm.nih.gov/pubmed/30487550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0186-9
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