Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway

Ginsenoside Rg1 (Rg1), a saponin extracted from Panax ginseng, has been well documented to be effective against ischemic/reperfusion (I/R) neuronal injury. However, the underlying mechanisms remain obscure. In the present study, we investigated the roles of Nrf2 and miR-144 in the protective effects...

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Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Chu, Shi-feng, Zhang, Zhao, Zhou, Xin, He, Wen-bin, Chen, Chen, Luo, Piao, Liu, Dan-dan, Ai, Qi-di, Gong, Hai-fan, Wang, Zhen-zhen, Sun, Hong-shuo, Feng, Zhong-ping, Chen, Nai-hong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318278/
https://ncbi.nlm.nih.gov/pubmed/30262824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0154-z
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