Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds

The brain-specific angiogenesis inhibitor (BAI) subfamily of adhesion G protein-coupled receptors (aGPCRs) plays crucial roles in diverse cellular processes including phagocytosis, myoblast fusion, and synaptic development through the ELMO/DOCK/Rac signaling pathway, although the underlying molecula...

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Vydáno v:Nat Commun
Hlavní autoři: Weng, Zhuangfeng, Situ, Chenghao, Lin, Lin, Wu, Zhenguo, Zhu, Jinwei, Zhang, Rongguang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318265/
https://ncbi.nlm.nih.gov/pubmed/30604775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07938-9
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