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Quantitative Evaluation of Native Protein Folds and Assemblies by Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS)

Hydrogen deuterium exchange mass spectrometry (HDX-MS) has significant potential for protein structure initiatives but its relationship with protein conformations is unclear. We report on the efficacy of HDX-MS to distinguish between native and non-native proteins using a popular approach to calcula...

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Vydáno v:J Am Soc Mass Spectrom
Hlavní autoři: Harris, Matthew J., Raghavan, Deepika, Borysik, Antoni J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318237/
https://ncbi.nlm.nih.gov/pubmed/30280315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-2070-3
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