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Therapeutic potential of Focal Adhesion Kinase inhibition in small cell lung cancer

Small cell lung cancer (SCLC) has a poor prognosis. Focal Adhesion Kinase (FAK) is a non-receptor tyrosine kinase regulating cell proliferation, survival, migration, and invasion, which is overexpressed and/or activated in several cancers, including SCLC. We wanted to determine whether FAK contribut...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Nana, Frank Aboubakar, Lecocq, Marylène, Ladjemi, Maha Zohra, Detry, Bruno, Dupasquier, Sébastien, Feron, Olivier, Massion, Pierre P., Sibille, Yves, Pilette, Charles, Ocak, Sebahat
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318062/
https://ncbi.nlm.nih.gov/pubmed/30352800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0328
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