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The circadian PER2 enhancer Nobiletin reverses the deleterious effects of midazolam in myocardial ischemia and reperfusion injury

BACKGROUND: Recently, we identified the circadian rhythm protein Period 2 (PER2) in robust cardioprotection from myocardial ischemia (MI). Based on findings that perioperative MI is the most common major cardiovascular complication and that anesthetics can alter the expression of PER2, we hypothesiz...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Pharm Des
Prif Awduron: Oyama, Yoshimasa, Bartman, Colleen Marie, Gile, Jennifer, Sehrt, Daniel, Eckle, Tobias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318050/
https://ncbi.nlm.nih.gov/pubmed/30246635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1381612824666180924102530
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