Hyperpolarized MRI visualizes Warburg effects and predicts treatment response to mTOR inhibitors in patient-derived ccRCC xenograft models

The ever-changing tumor-microenvironment constantly challenges individual cancer cells to balance supply and demand, presenting tumor vulnerabilities and therapeutic opportunities. Everolimus and temsirolimus are inhibitors of mTOR (mTORi) approved for treating metastatic renal cell carcinoma (mRCC)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Dong, Yiyu, Eskandari, Roozbeh, Ray, Chelsea, Granlund, Kristin L., Santos-Cunha, Lidia Dos, Miloushev, Vesselin Z., Tee, Sui Seng, Jeong, Sangmoo, Aras, Omer, Chen, Ying-Bei, Cheng, Emily H., Hsieh, James J., Keshari, Kayvan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318024/
https://ncbi.nlm.nih.gov/pubmed/30459151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2231
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