Mutational activation of the epidermal growth factor receptor down‐regulates major histocompatibility complex class I expression via the extracellular signal‐regulated kinase in non–small cell lung cancer

The efficacy of programmed cell death–1 (PD‐1) blockade in patients with non–small cell lung cancer (NSCLC) positive for epidermal growth factor receptor (EGFR) gene mutations has been found to be limited, but the underlying mechanisms for this poor response have remained obscure. Given that the rec...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Watanabe, Satomi, Hayashi, Hidetoshi, Haratani, Koji, Shimizu, Shigeki, Tanizaki, Junko, Sakai, Kazuko, Kawakami, Hisato, Yonesaka, Kimio, Tsurutani, Junji, Togashi, Yosuke, Nishio, Kazuto, Ito, Akihiko, Nakagawa, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317949/
https://ncbi.nlm.nih.gov/pubmed/30390416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13860
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