Palbociclib enhances activin‐SMAD‐induced cytostasis in estrogen receptor‐positive breast cancer

Cyclin‐dependent kinase (CDK) 4 and CDK6 inhibitors are effective therapeutic options for hormone receptor (HR)‐positive, human epidermal growth factor receptor 2 (HER2)‐negative advanced breast cancer. Although CDK4/6 inhibitors mainly target the cyclin D‐CDK4/6‐retinoblastoma tumor suppressor prot...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Harada, Mayumi, Morikawa, Masato, Ozawa, Takayuki, Kobayashi, Mai, Tamura, Yusuke, Takahashi, Kei, Tanabe, Masahiko, Tada, Keiichiro, Seto, Yasuyuki, Miyazono, Kohei, Koinuma, Daizo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317929/
https://ncbi.nlm.nih.gov/pubmed/30343527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13841
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