PD‐L1 expression enhancement by infiltrating macrophage‐derived tumor necrosis factor‐α leads to poor pancreatic cancer prognosis

Immunotherapy using anti‐PD‐1/PD‐L1 antibodies for several types of cancer has received considerable attention in recent decades. However, the molecular mechanism underlying PD‐L1 expression in pancreatic ductal adenocarcinoma (PDAC) cells has not been clearly elucidated. We investigated the clinica...

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Vydáno v:Cancer Sci
Hlavní autoři: Tsukamoto, Masayo, Imai, Katsunori, Ishimoto, Takatsugu, Komohara, Yoshihiro, Yamashita, Yo‐ichi, Nakagawa, Shigeki, Umezaki, Naoki, Yamao, Takanobu, Kitano, Yuki, Miyata, Tatsunori, Arima, Kota, Okabe, Hirohisa, Baba, Yoshifumi, Chikamoto, Akira, Ishiko, Takatoshi, Hirota, Masahiko, Baba, Hideo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317925/
https://ncbi.nlm.nih.gov/pubmed/30426611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13874
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