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CRISPR/Cas9-mediated kif15 mutations accelerate axonal outgrowth during neuronal development and regeneration in zebrafish

KIF15, the vertebrate kinesin-12, is best known as a mitotic motor protein, but continues to be expressed in neurons. Like KIF11 (the vertebrate kinesin-5), KIF15 interacts with microtubules in the axon to limit their sliding relative to one another. Unlike KIF11, KIF15 also regulates interactions b...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Dong, Zhangji, Wu, Shuwen, Zhu, Chenwen, Wang, Xueting, Li, Yuanyuan, Chen, Xu, Liu, Dong, Qiang, Liang, Baas, Peter W., Liu, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317882/
https://ncbi.nlm.nih.gov/pubmed/30411440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12621
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