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Metabolic pathway activation distinguish transcriptional signatures of CD8(+) T cells from HIV-1 elite controllers

OBJECTIVE: Elite controllers (EC), defined as persons maintaining undetectable levels of HIV-1 replication in the absence of antiretroviral therapy, represent living evidence that sustained, natural control of HIV-1 is possible, at least in relatively rare instances. Understanding the complex immuno...

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Vydáno v:AIDS
Hlavní autoři: CHOWDHURY, Fatema Z., OUYANG, Zhengyu, BUZON, Maria, WALKER, Bruce D., LICHTERFELD, Mathias, YU, Xu G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317861/
https://ncbi.nlm.nih.gov/pubmed/30289807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002007
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