Pentraxin 3 deletion aggravates allergic inflammation through a T(H)17-dominant phenotype and enhanced CD4 T-cell survival

BACKGROUND: Pentraxin 3 (PTX3) is a multifunctional molecule that plays a nonredundant role at the crossroads between pathogen clearance, innate immune system, matrix deposition, female fertility, and vascular biology. It is produced at sites of infection and inflammation by both structural and infl...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Balhara, Jyoti, Shan, Lianyu, Zhang, Jingbo, Muhuri, Anik, Halayko, Andrew J., Almiski, Muhamad S., Doeing, Diana, McConville, John, Matzuk, Martin M., Gounni, Abdelilah S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Allergy, Asthma & Immunology 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317853/
https://ncbi.nlm.nih.gov/pubmed/27567326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.04.063
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