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Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells

Dynamin copolymerizes with cortactin to form a ring-like complex that bundles and stabilizes actin filaments. Actin bundle formation is crucial for generation of filopodia and lamellipodia, which guide migration, invasion, and metastasis of cancer cells. However, it is unknown how the dynamin-cortac...

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Dades bibliogràfiques
Publicat a:Int J Oncol
Autors principals: Abe, Tadashi, La, The Mon, Miyagaki, Yuuzi, Oya, Eri, Wei, Fan-Yan, Sumida, Kento, Fujise, Kenshiro, Takeda, Tetsuya, Tomizawa, Kazuhito, Takei, Kohji, Yamada, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317663/
https://ncbi.nlm.nih.gov/pubmed/30570111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4663
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