Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells

Dynamin copolymerizes with cortactin to form a ring-like complex that bundles and stabilizes actin filaments. Actin bundle formation is crucial for generation of filopodia and lamellipodia, which guide migration, invasion, and metastasis of cancer cells. However, it is unknown how the dynamin-cortac...

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Bibliographic Details
Published in:Int J Oncol
Main Authors: Abe, Tadashi, La, The Mon, Miyagaki, Yuuzi, Oya, Eri, Wei, Fan-Yan, Sumida, Kento, Fujise, Kenshiro, Takeda, Tetsuya, Tomizawa, Kazuhito, Takei, Kohji, Yamada, Hiroshi
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317663/
https://ncbi.nlm.nih.gov/pubmed/30570111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4663
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