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IRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway
BACKGROUND: Interferon regulatory factor 1 (IRF1) plays a role in the immune response, cellular necrosis, DNA damage, and DNA repair, offering an attractive target for anticancer treatment. However, little is known about the role of IRF1 in the regulation of CRC progression. METHODS: Quantitative re...
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| Veröffentlicht in: | Cancer Manag Res |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317468/ https://ncbi.nlm.nih.gov/pubmed/30643462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S186236 |
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