IRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway

BACKGROUND: Interferon regulatory factor 1 (IRF1) plays a role in the immune response, cellular necrosis, DNA damage, and DNA repair, offering an attractive target for anticancer treatment. However, little is known about the role of IRF1 in the regulation of CRC progression. METHODS: Quantitative re...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Hong, Min, Zhang, Zuoyang, Chen, Qing, Lu, Yanxia, Zhang, Jianming, Lin, Chun, Zhang, Fan, Zhang, Wenjuan, Li, Xiaomin, Zhang, Wei, Li, Xuenong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317468/
https://ncbi.nlm.nih.gov/pubmed/30643462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S186236
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