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Single-particle reconstruction statistics: a diagnostic tool in solving biomolecular structures by cryo-EM

In single-particle analysis (SPA), the aim is to obtain a 3D reconstruction of a biological molecule from 2D electron micrographs to the highest level of detail or resolution as possible. Current practice is to collect large volumes of data, hoping to reach high-resolution maps through sheer numbers...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Autor principal: Heymann, J. Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317460/
https://ncbi.nlm.nih.gov/pubmed/30605123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18017636
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