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Evolving imprinting control regions: KRAB zinc fingers hold the key

The monoallelic parent of origin-specific expression of imprinted genes in mammals is regulated by differentially DNA methylated imprinting control regions (ICRs). In contrast to most of the genome, ICRs must maintain their DNA methylation and parental identity despite extensive epigenetic reprogram...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Juan, Aimee M., Bartolomei, Marisa S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317316/
https://ncbi.nlm.nih.gov/pubmed/30602436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.322990.118
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