STAT3 enhances the constitutive activity of AGC kinases in melanoma by transactivating PDK1

BACKGROUND: The PI3K/Akt and the STAT3 pathways are functionally associated in many tumor types. Both in vitro and in vivo studies have revealed that either biochemical or genetic manipulation of the STAT3 pathway activity induce changes in the same direction in Akt activity. However, the implicated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Biosci
Egile Nagusiak: Picco, María Elisa, Castro, María Victoria, Quezada, María Josefina, Barbero, Gastón, Villanueva, María Belén, Fernández, Natalia Brenda, Kim, Hyungsoo, Lopez-Bergami, Pablo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317239/
https://ncbi.nlm.nih.gov/pubmed/30622697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-018-0265-8
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