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Structural Features and Binding Modes of Thioether-Cyclized Peptide Ligands

Macrocyclic peptides are an emerging class of bioactive compounds for therapeutic use. In part, this is because they are capable of high potency and excellent target affinity and selectivity. Over the last decade, several biochemical techniques have been developed for the identification of bioactive...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Otero-Ramirez, Manuel E., Passioura, Toby, Suga, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316662/
https://ncbi.nlm.nih.gov/pubmed/30551606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6040116
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